Biochemical Changes in Experimental Rat Model of Abdominal Compartment Syndrome
نویسندگان
چکیده
منابع مشابه
Developing a new experimental model of abdominal compartment syndrome.
OBJECTIVE To describe an experimental, unprecedented model that mimics the abdominal compartment syndrome (ACS). METHODS twenty rats were randomly divided into four groups. To simulate ACS intra-abdominal hypertension (IAH) was induced by inserting cotton surgical dressing (Zobec ®), 15x15cm (intra-abdominal pressure constant and equal to 12 mmHg) associated with hypovolemia induced by withdr...
متن کاملAbdominal compartment syndrome
Intra-abdominal hypertension (IAH) associated with organ dysfunction defines the abdominal compartment syndrome (ACS). Elevated intra-abdominal pressure (IAP) adversely impacts pulmonary, cardiovascular, renal, splanchnic, musculoskeletal/integumentary, and central nervous system physiology. The combination of IAH and disordered physiology results in a clinical syndrome with significant morbidi...
متن کاملAbdominal compartment syndrome.
Acute renal failure frequently occurs in the intensive care unit as a primary or secondary event in association with trauma, surgery, or comorbid medical disease. An increasingly common thread linking surgical and medical disease management is the abdominal compartment syndrome. In particular, the rise of early goal-directed therapy for the initial resuscitation and management of severe sepsis ...
متن کاملAbdominal Compartment Syndrome
Abdominal compartment syndrome is a potentially lethal condition caused by any event that produces intra-abdominal hypertension; the most common cause is blunt abdominal trauma. Increasing intraabdominal pressure causes progressive hypoperfusion and ischemia of the intestines and other peritoneal and retroperitoneal structures. Pathophysiological effects include release of cytokines, formation ...
متن کاملAbdominal compartment syndrome
Various systems are involved in this syndrome. First, the increased intra-abdominal pressure is transmitted to the pleural space so that lung compliance decreases. Hypoventilation and alteration of ventilation/perfusion distribution lead to hypoxemia and hypercapnia. When mechanical ventilation is applied, very high inspiratory pressures are often required to deliver tidal volume. Second, the c...
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ژورنال
عنوان ژورنال: Folia Medica
سال: 2017
ISSN: 1314-2143
DOI: 10.1515/folmed-2017-0056